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Antibodies

AMG-966

Product Sizes
1 mg
£ POA
HY-P991440-1MG
10 mg
£ POA
HY-P991440-10MG
25 mg
£ POA
HY-P991440-25MG
5 mg
£ POA
HY-P991440-5MG
About this Product
SKU:
HY-P991440
Extra Details:
AMG-966 is a human bispecific antibody (bsAb) targeting TNFSF15/TL1A & TNFα. AMG 966 restores the ability of the aglycosylated Fc domain to bind FcγRIa and FcγRIIa; leading to the formation of anti-drug antibodies (ADA). AMG 966 can be used in research on Crohn's disease and ulcerative colitis. Recommended isotype control: Human IgG1 kappa; Isotype Control (HY-P99001)[1].
Molecular Weight:
(145.25 kDa)
Purity:
96.19
References:
[1]Kroenke MA, et al. Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target. Front Immunol. 2021 Dec 14;12:782788.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Dry Ice
Storage Conditions:
-80[o]C
Type:
Antibodies
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