AT-1413
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HY-P991425-1EACH
About this Product
- SKU:
- HY-P991425
- Application:
- Antibody Microarray
- Extra Details:
- AT-1413 is a human monoclonal antibody (mAb) targeting CD43. AT-1413 induces antibody-dependent cell-mediated cytotoxicity (ADCC) in melanoma cell lines and acute myeloid leukemia (AML) cells. AT-1413 has antitumor activity in AML mouse models. AT-1413 can be used in Acute myeloid leukaemia; Breast cancer; Malignant melanoma and Myelodysplastic syndromes research. Recommended isotype control: Human IgG1 kappa; Isotype Control (HY-P99001)[1].
- References:
- [1]De Jong G, et al. PS971 AT1413 ANTIBODY DERIVED FROM A CURED AML PATIENT RECOGNIZES A UNIQUE CD43 EPITOPE SHARED BY AML, MDS AND MELANOMA AND HAS IN VIVO ACTIVITY AS UNMODIFIED ANTIBODY AND AS BISPECIFIC T CELL ENGAGER[J]. HemaSphere, 2019, 3: 437-438.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Antibodies
