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Antibodies

MK-1248

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HY-P991406-1EACH
About this Product
SKU:
HY-P991406
Application:
Antibody Microarray
Extra Details:
MK-1248 is a human IgG4 monoclonal antibody (mAb) targeting TNFSF18. MK-1248 enhances the proliferative response of tumor-infiltrating lymphocytes to anti-CD3 stimulation and promotes the production of anti-tumor-associated regulatory cytokines. MK-1248 can be used in solid tumors research[1].
References:
[1]Geva R, et al. First-in-human phase 1 study of MK-1248, an anti-glucocorticoid-induced tumor necrosis factor receptor agonist monoclonal antibody, as monotherapy or with pembrolizumab in patients with advanced solid tumors. Cancer. 2020 Nov 15;126(22):4926-4935.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Antibodies
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