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Antibodies

AMG-529

Product Sizes
5 mg
£ POA
HY-P991222-5MG
10 mg
£ POA
HY-P991222-10MG
1 mg
£ POA
HY-P991222-1MG
About this Product
SKU:
HY-P991222
Application:
Immunoprecipitation
Extra Details:
AMG-529 is a humanized monoclonal antibody against ASGR1 that binds to ASGR1; blocks ligand binding; and causes a dose-dependent increase in ALP (a biomarker of ASGR1 inhibition). AMG-529 can be used for the research of cardiovascular diseases[1].
Molecular Weight:
(146.44 kDa)
Purity:
97.41
References:
[1]Janiszewski, M.,et al. A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING SINGLE-DOSE, PHASE 1 STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF AMG 529, A NOVEL ANTI-ASGR1 MONOCLONAL ANTIBODY, IN HEALTHY SUBJECTS. Journal of the American College of Cardiology, 73(9), 1755.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Dry Ice
Storage Conditions:
-80[o]C
Type:
Antibodies
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