AL002
Product Sizes
10 mg
£ POA
HY-P991220-10MG
5 mg
£ POA
HY-P991220-5MG
1 mg
£ POA
HY-P991220-1MG
About this Product
- SKU:
- HY-P991220
- Extra Details:
- AL002 is a humanized monoclonal IgG1 antibody and a blood-brain barrier-permeable TREM2 modulator. AL002 binds to TREM2 on the surface of microglia; promotes TREM2 clustering and the formation of the TREM2-DAP12 complex; activates the TREM2 signaling pathway and PI3K cascade; and induces TREM2 internalization and degradation. AL002 is applicable to research related to Alzheimer's disease[1][2].
- Molecular Weight:
- (145.62 kDa)
- Purity:
- 98.01
- References:
- [1]Hua Long, et al. Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer's disease. Alzheimers Res Ther. 2024 Oct 23;16(1):235.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -80[o]C
- Type:
- Antibodies
