ADG-106
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HY-P991070-1EACH
About this Product
- SKU:
- HY-P991070
- Application:
- Antibody Microarray
- Extra Details:
- ADG-106 is a fully human agonistic monoclonal IgG4 antibody against CD137 (4-1BB). ADG-106 has the mechanism to activate CD137 via strong FcγRIIB-mediated crosslinking while antagonizing CD137 ligands. The isotype control for ADG-106 can refer to Human IgG4 (S228P) kappa; Isotype Control (HY-P99003)[1].
- References:
- [1]Ma Y, et al. Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin's lymphoma. Cell Rep Med. 2024 Feb 20;5(2):101414.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Antibodies
