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Antibodies

Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2)

Product Sizes
1 mg
£ POA
HY-P990172-1MG
10 mg
£ POA
HY-P990172-10MG
5 mg
£ POA
HY-P990172-5MG
About this Product
SKU:
HY-P990172
Extra Details:
Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) is a recombinant chimeric version of the original 10F.9G2 antibody (HY-P99145). The variable domain sequences are identical to the original 10F.9G2 but the constant region sequences have been switched from rat IgG2b to mouse IgG1. Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) contains a D265A mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) blocks PD-1 signaling. Anti-Mouse PD-L1/B7-H1 (D265A) Antibody (10F.9G2) can be used for the research of cancer.
Molecular Weight:
(143.882 kDa)
Purity:
99.32
References:
[1]Goulet DR, Atkins WM. Considerations for the Design of Antibody-Based Therapeutics. J Pharm Sci. 2020 Jan;109(1):74-103.
Research Area:
Cancer
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -80[o]C for 2 years
Type:
Antibodies
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