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Antibodies

Amatuximab

Product Sizes
1 mg
£ POA
HY-P99006-1MG
10 mg
£ POA
HY-P99006-10MG
5 mg
£ POA
HY-P99006-5MG
25 mg
£ POA
HY-P99006-25MG
100 mg
£ POA
HY-P99006-100MG
50 mg
£ POA
HY-P99006-50MG
About this Product
SKU:
HY-P99006
Additional Names:
MORab-009
Application:
Antibody Microarray
CAS Number:
931402-35-6
Extra Details:
Amatuximab (MORab-009) is a chimeric; humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein; which is present in a restricted set of normal adult tissues such as the mesothelium[1][2].
Molecular Weight:
(144.363 kDa)
Purity:
99.90
References:
[1]Hassan R, et al. Phase II clinical trial of amatuximab, a chimeric antimesothelin antibody with pemetrexed and cisplatin in advanced unresectable pleural mesothelioma. Clin Cancer Res. 2014;20(23):5927-5936. |[2]Baldo P, et al. Amatuximab and novel agents targeting mesothelin for solid tumors. Onco Targets Ther. 2017;10:5337-5353. Published 2017 Nov 8.
Research Area:
Cancer
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -80[o]C for 2 years
Type:
Antibodies
Pathway:
Immunology/Inflammation
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