AITRL/TNFSF18; Mouse (HEK293; Fc)
Product Sizes
50 μg
£ POA
HY-P78299-50UG
20 μg
£ POA
HY-P78299-20UG
About this Product
- SKU:
- HY-P78299
- Additional Names:
- AITRL/TNFSF18 Protein; Mouse (HEK293; Fc);Mouse;HEK293
- Extra Details:
- AITRL; a type II transmembrane protein; is a ligand for glucocorticoid-induced TNFR-related protein (GITR). When AITRL binds to GITR; GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions. GITR/AITRL interaction plays a role in the pathogenesis of tumor; inflammation; as well as autoimmune diseases[1]. Besides; AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1; ICAM-1)[2]. AITRL/TNFSF18 Protein; Mouse (HEK293; Fc) is a recombinant mouse AITRL (T47-S173) with N-terminal hFc tag; which is expressed in HEK293.
- Molecular Weight:
- Approximately 50-60 kDa; based on SDS-PAGE under reducing conditions; due to the glycosylation.
- Purity:
- 95.00
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
