Cynomolgus IL-23 alpha & Mouse IL-12 beta Heterodimer (HEK293; His)
Product Sizes
50 μg
£ POA
HY-P77703-50UG
20 μg
£ POA
HY-P77703-20UG
About this Product
- SKU:
- HY-P77703
- Additional Names:
- Cynomolgus IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293; His);Cynomolgus;HEK293
- Extra Details:
- IL-23 alpha and IL-12 beta are the IL-23p19 and IL-12p40 subunits; respectively; composing IL-23 via heterodimerization manner. IL-23 binds to a heterodimeric receptor composed of IL-12RB1 and IL-23R; activates the Jak-Stat signaling cascade; acts on memory CD4(+) T cells preferentially[1]. IL-23 also involves in activation of several pathways including p38 MAPK or NF-κB and promotes the production of pro-inflammatory cytokines such as interleukin-17A/IL17A[2]. Cynomolgus IL-23 alpha & Mouse IL-12 beta Heterodimer Protein is produced in HEK293 cells; with total length of 481 amino acids and a N-Terminal His-tag.
- Molecular Weight:
- 22 ( Cynomolgus IL23 alpha)&40-50 (Mouse IL12 beta) kDa
- Purity:
- 95.0
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
