DR6/TNFRSF21; Cynomolgus (HEK293; His)
Product Sizes
50 μg
£ POA
HY-P77352-50UG
2 μg
£ POA
HY-P77352-2UG
10 μg
£ POA
HY-P77352-10UG
100 μg
£ POA
HY-P77352-100UG
About this Product
- SKU:
- HY-P77352
- Additional Names:
- DR6/TNFRSF21 Protein; Cynomolgus (HEK293; His);Cynomolgus;HEK293
- Extra Details:
- Tnfrsf21 Protein; also known as death receptor 6 (DR6); CD358; or BM-018; is highly expressed in differentiating neurons as well as in the adult brain; and is upregulated in injured neurons. DR6 negatively regulates neuron; axon; and oligodendrocyte survival; hinders axondendrocyte and oligodendrocyte regeneration and its inhibition has a neuro-protective effect in nerve injury. It activates nuclear factor kappa-B (NFkB) and mitogen-activated protein kinase 8 (MAPK8; also called c-Jun N-terminal kinase 1); and induces cell apoptosis by associating with TNFRSF1A-associated via death domain (TRADD); which is known to mediate signal transduction of tumor necrosis factor receptors. DR6/TNFRSF21 Protein; Cynomolgus (HEK293; His) is the recombinant cynomolgus-derived DR6/TNFRSF21 protein; expressed by HEK293 ; with C-His labeled tag.
- Molecular Weight:
- Approximately 55-75 kDa; based on SDS-PAGE under reducing conditions.
- Purity:
- 96.00
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
