IL-2R alpha/CD25; Cynomolgus (HEK293; Fc)
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HY-P76786-1EACH
About this Product
- SKU:
- HY-P76786
- Additional Names:
- IL-2R alpha/CD25 Protein; Cynomolgus (HEK293; Fc);Cynomolgus;HEK293
- Extra Details:
- IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions[1][2]. IL-2R alpha/CD25 Protein; Cynomolgus (HEK293; Fc) is a recombinant cynomolgus IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213).
- Molecular Weight:
- Approximately 65 kDa;based on SDS-PAGE under reducing conditions.
- References:
- [1]H.Asao. Interleukin-2. Reference Module in Biomedical Sciences. 2014. ISBN 9780128012383.|[2]Kim HP, et al. The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements. Immunity. 2001 Jul;15(1):159-72.|[3]Bell CJ, et al. Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells. J Autoimmun. 2015 Jan;56:66-80.|[4]Chistiakov DA, et al. The crucial role of IL-2/IL-2RA-mediated immune regulation in the pathogenesis of type 1 diabetes, an evidence coming from genetic and animal model studies. Immunol Lett. 2008 Jun 15;118(1):1-5.
- Shipping Conditions:
- Dry Ice
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
