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Proteins and Peptides

GITR; Cynomolgus (HEK293; His)

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HY-P76362-1EACH
About this Product
SKU:
HY-P76362
Additional Names:
GITR Protein; Cynomolgus (HEK293; His);Cynomolgus;HEK293
Extra Details:
GITR (TNFRSF18) is a member of the TNFR superfamily. GITR promotes T cell activation and proliferation and increases resistance to tumors and viral infections; and exacerbates autoimmune diseases and inflammation processes[1]. GITR Protein; Cynomolgus (HEK293; His) is a recombinant protein with a C-terminal His label; It consists of 155 amino acids (M1-E155) and is produced in HEK293 cells.
References:
[1]Tian J, et al. The Role of GITR/GITRL Interaction in Autoimmune Diseases. Front Immunol. 2020 Oct 9;11:588682.|[2]Krausz LT, et al. GITR-GITRL system, a novel player in shock and inflammation. ScientificWorldJournal. 2007 May 1;7:533-66.|[3]Shin HH, et al. Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage. FEBS Lett. 2002 Mar 13;514(2-3):275-80.|[4]Liu Y, et al. Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma. PLoS One. 2013 Jun 13;8(6):e66982.
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
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