ALK-7; Rhesus Macaque (HEK293; Fc)
Product Sizes
1 mg
£ POA
HY-P75573-1MG
2 μg
£ POA
HY-P75573-2UG
10 μg
£ POA
HY-P75573-10UG
100 μg
£ POA
HY-P75573-100UG
500 μg
£ POA
HY-P75573-500UG
50 μg
£ POA
HY-P75573-50UG
About this Product
- SKU:
- HY-P75573
- Additional Names:
- ALK-7 Protein; Rhesus Macaque (HEK293; Fc);Rhesus Macaque;HEK293
- Extra Details:
- ALK-7 is a type I receptor serine-threonine kinase mediate inhibitory as well as stimulatory signals for growth and differentiation by binding to members of the TGF-β superfamily. ALK-7 combined with specific ligands; such as Nodal; activin B and growth differentiation factor (GDF); can activate Smads and other signaling pathways; thereby regulating cell proliferation; differentiation and apoptosis in various cells[1][2][3]. ALK-7 Protein; Rhesus Macaque (HEK293; Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 89 amino acids (G25-E113).
- Molecular Weight:
- Approximately 43-70 kDa due to the glycosylation.
- Purity:
- 95.00
- References:
- [1]M Rydén, et al. A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system. J Biol Chem. 1996 Nov 29;271(48):30603-9.|[2]Byung-Chul Kim, et al. Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells. J Biol Chem. 2004 Jul 2;279(27):28458-65.|[3]Wen-bo Li, et al. Silencing of activin receptor-like kinase 7 alleviates aortic stiffness in type 2 diabetic rats. Acta Diabetol. 2015 Aug;52(4):717-26.|[4]Kunihiro Tsuchida, et al. Activin isoforms signal through type I receptor serine/threonine kinase ALK7. Mol Cell Endocrinol. 2004 May 31;220(1-2):59-65.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
