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Proteins and Peptides

ACVR2A/Activin RIIA; Mouse (HEK293; His)

Product Sizes
1 mg
£ POA
HY-P75563-1MG
5 μg
£ POA
HY-P75563-5UG
10 μg
£ POA
HY-P75563-10UG
50 μg
£ POA
HY-P75563-50UG
500 μg
£ POA
HY-P75563-500UG
100 μg
£ POA
HY-P75563-100UG
About this Product
SKU:
HY-P75563
Additional Names:
ACVR2A/Activin RIIA Protein; Mouse (HEK293; His);Mouse;HEK293
Extra Details:
ACVR2A; also known as Activin RIIA; is an activin type II receptor. On ligand binding; ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. ACVR2A is a receptor for Activin A; Activin B and Inhibin A[1][2]. ACVR2A/Activin RIIA Protein; Mouse (HEK293; His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 134 amino acids (M1-P134).
Molecular Weight:
Approximately 35 kDa
Purity:
95.80
References:
[1]Oddrun Elise Olsen, et al. Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B. Cell Commun Signal. 2015 Jun 6;13:27.|[2]V K Chin, et al. Inhibition of Activin A suppressed tumor necrosis factor-α secretion and improved histopathological conditions in malarial mice. Trop Biomed. 2021 Mar 1;38(1):187-204.|[3]Szabina Szófia Szilágyi, et al. Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways. BMC Biol. 2022 Feb 18;20(1):50.|[4]Heather L Hayes, et al. A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation. Mol Cell Biol. 2016 Nov 14;36(23):2918-2930.
Shipping Conditions:
Ambient
Storage Conditions:
Stored at -20[o]C for 2 years
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
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