ACVR1; Mouse (HEK293; His-hFc)
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HY-P75539-1EACH
About this Product
- SKU:
- HY-P75539
- Additional Names:
- ACVR1 Protein; Mouse (HEK293; His-hFc);Mouse;HEK293
- Extra Details:
- Activin A receptor; type I (ACVR1); also known as ALK-2; is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes; including bone; heart; cartilage; nervous; and reproductive system development and regulation[1]. ACVR1 Protein; Mouse (HEK293; His-hFc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag . It consists of 123 amino acids (M1-E123).
- Molecular Weight:
- Approximately 45 kDa;based on SDS-PAGE under reducing conditions;due to the glycosylation.
- References:
- [1]José Antonio Valer, et al. ACVR1 Function in Health and Disease. Cells. 2019 Oct 31;8(11):1366.|[2]Jing Pang, et al. ACVR1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossificans progressive. Bone. 2016 Nov;92:29-36.
- Shipping Conditions:
- Dry Ice
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
