ACVR2A/Activin RIIA; Human/Cynomolgus (HEK293; Fc)
Product Sizes
1 mg
£ POA
HY-P75537-1MG
2 μg
£ POA
HY-P75537-2UG
10 μg
£ POA
HY-P75537-10UG
500 μg
£ POA
HY-P75537-500UG
50 μg
£ POA
HY-P75537-50UG
100 μg
£ POA
HY-P75537-100UG
About this Product
- SKU:
- HY-P75537
- Additional Names:
- ACVR2A/Activin RIIA Protein; Human/Cynomolgus (HEK293; Fc);Human;Cynomolgus;HEK293
- Extra Details:
- ACVR2A; also known as Activin RIIA; is an activin type II receptor. On ligand binding; ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. ACVR2A is a receptor for Activin A; Activin B and Inhibin A[1][2]. ACVR2A/Activin RIIA Protein; Human/Cynomolgus (HEK293; Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 134 amino acids (M1-P134).
- Molecular Weight:
- Approximately 55-70kDa due to the glycosylation.
- Purity:
- 96.00
- References:
- [2]V K Chin, et al. Inhibition of Activin A suppressed tumor necrosis factor-α secretion and improved histopathological conditions in malarial mice. Trop Biomed. 2021 Mar 1;38(1):187-204.|[3]Szabina Szófia Szilágyi, et al. Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways. BMC Biol. 2022 Feb 18;20(1):50.|[4]Heather L Hayes, et al. A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation. Mol Cell Biol. 2016 Nov 14;36(23):2918-2930.|[1]Oddrun Elise Olsen, et al. Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B. Cell Commun Signal. 2015 Jun 6;13:27.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
