ALK-1; Canine (HEK293; Fc)
Product Sizes
1 mg
£ POA
HY-P75516-1MG
2 μg
£ POA
HY-P75516-2UG
10 μg
£ POA
HY-P75516-10UG
50 μg
£ POA
HY-P75516-50UG
100 μg
£ POA
HY-P75516-100UG
500 μg
£ POA
HY-P75516-500UG
About this Product
- SKU:
- HY-P75516
- Additional Names:
- ALK-1 Protein; Canine (HEK293; Fc);Canine;HEK293
- Extra Details:
- ALK-1; also known as ACVRL1; is a type I receptor for TGF-β superfamily with 2 ligands; BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis[1][2]. ALK-1 Protein; Canine (HEK293; Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 119 amino acids (M1-K119).
- Molecular Weight:
- 43-47 kDa
- Purity:
- 98.00
- References:
- [1]S P Oh, et al. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2626-31.|[2]Dianyuan Zhao, et al. ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection. J Clin Invest. 2022 Feb 1;132(3):e150489.|[3]Dianne Mitchell, et al. ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth. Mol Cancer Ther. 2010 Feb;9(2):379-88.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
