GITR; Human (Biotinylated; HEK293; Fc-Avi)
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HY-P75166-1EACH
About this Product
- SKU:
- HY-P75166
- Additional Names:
- GITR Protein; Human (Biotinylated; HEK293; Fc-Avi);Human;HEK293
- Extra Details:
- GITR (TNFRSF18) is a member of the TNFR superfamily. GITR promotes T cell activation and proliferation and increases resistance to tumors and viral infections; and exacerbates autoimmune diseases and inflammation processes[1]. GITR Protein; Human (Biotinylated; HEK293; Fc-Avi) is a recombinant protein with a C-terminal Fc label and a C-terminal Avi label; It consists of 161 amino acids (M1-E161) and is produced in HEK293 cells.
- References:
- [1]Tian J, et al. The Role of GITR/GITRL Interaction in Autoimmune Diseases. Front Immunol. 2020 Oct 9;11:588682.|[2]Krausz LT, et al. GITR-GITRL system, a novel player in shock and inflammation. ScientificWorldJournal. 2007 May 1;7:533-66.|[3]Shin HH, et al. Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage. FEBS Lett. 2002 Mar 13;514(2-3):275-80.|[4]Liu Y, et al. Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma. PLoS One. 2013 Jun 13;8(6):e66982.
- Shipping Conditions:
- Dry Ice
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
