IL-2R alpha/CD25; Rat (sf9; His)
Product Sizes
50 μg
£ POA
HY-P74809-50UG
About this Product
- SKU:
- HY-P74809
- Additional Names:
- IL-2R alpha/CD25 Protein; Rat (sf9; His);Rat;Sf9 insect cells
- Extra Details:
- IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions[1][2]. IL-2R alpha/CD25 Protein; Rat (sf9; His) is a recombinant rat IL-2R alpha protein with a His tag at the C-terminus and is expressed in Sf9 insect cells.
- Molecular Weight:
- Approximately 40 kDa;based on SDS-PAGE under reducing conditions.
- Purity:
- 99
- References:
- [1]H.Asao. Interleukin-2. Reference Module in Biomedical Sciences. 2014. ISBN 9780128012383.|[2]Kim HP, et al. The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements. Immunity. 2001 Jul;15(1):159-72.|[3]Bell CJ, et al. Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells. J Autoimmun. 2015 Jan;56:66-80.|[4]Chistiakov DA, et al. The crucial role of IL-2/IL-2RA-mediated immune regulation in the pathogenesis of type 1 diabetes, an evidence coming from genetic and animal model studies. Immunol Lett. 2008 Jun 15;118(1):1-5.|[5]Stephens LA, et al. CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations. J Immunol. 2000 Sep 15;165(6):3105-10.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Stored at -80[o]C for 1 year
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
