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Proteins and Peptides

BDNF; Mouse (R129A; R130A; HEK293; His; Solution))

Product Sizes
50 μg
£ POA
HY-P74383-50UG
10 μg
£ POA
HY-P74383-10UG
2 μg
£ POA
HY-P74383-2UG
5 μg
£ POA
HY-P74383-5UG
About this Product
SKU:
HY-P74383
Additional Names:
BDNF Protein; Mouse (R129A; R130A; HEK293; His; Solution);Mouse;HEK293
Extra Details:
Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that belongs to NGF-beta family. BDNF can bind to its high affinity receptor TrkB and activates signal transduction cascades (IRS1/2; PI3K; Akt)[1]. BDNF can also bind to the p75NTR; but the affinity for the p75NTR receptor is lower than for TrkB[2]. BDNF is a neurotransmitter modulator; and is vital in maturation; survival and differentiation of neuronal populations during development. BDNF also participates in neuronal plasticity; which is essential for learning and memory. BDNF is widely expressed in the CNS[1]. BDNF Protein; Mouse (R129A; R130A; HEK293; His) is a recombinant mouse BDNF (M1-R249; R129A; R130A) with C-terminal His tag; which is produced in HEK293.
Molecular Weight:
Approximately 35-45 kDa; based on SDS-PAGE under reducing conditions; due to the glycosylation.
Purity:
98.0
Shipping Conditions:
Dry Ice
Storage Conditions:
Stored at -80[o]C for 1 year
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
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