PD-L1; Human (HEK293; His)
Product Sizes
1 mg
HY-P7398-1MG
500 μg
HY-P7398-500UG
50 μg
HY-P7398-50UG
100 μg
HY-P7398-100UG
10 μg
HY-P7398-10UG
5 μg
HY-P7398-5UG
About this Product
- SKU:
- HY-P7398
- Additional Names:
- PD-L1 Protein; Human (HEK293; His);Human;HEK293
- Extra Details:
- PD-L1 Protein is an important immunoregulatory molecule and a member of the B7 superfamily. As the primary ligand of PD-1; PD-L1 Protein can bind to PD-1 to inhibit T-cell activation; proliferation; and cytokine secretion; and induce T-cell apoptosis. PD-L1 Protein plays a key role in tumor immune escape and immune homeostasis regulation. PD-L1 Protein; Human (HEK293; His) is a recombinant PD-L1 protein expressed by HEK293 with a C-His His tag[1][2][3].
- Molecular Weight:
- Approximately 35-40 kDa; based on SDS-PAGE under reducing condition; due to the glycosylation.
- Purity:
- 98.0
- References:
- [1]Chemnitz JM, et al. SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol. 2004 Jul 15;173(2):945-54.|[2]Han Y, et al. PD-1/PD-L1 pathway: current researches in cancer. Am J Cancer Res. 2020 Mar 1;10(3):727-742.|[3]Kythreotou A, et al. PD-L1. Journal of clinical pathology, 2018, 71(3): 189-194.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
