PD-L1; Canine (HEK293; Fc)
Product Sizes
50 μg
£ POA
HY-P73717-50UG
10 μg
£ POA
HY-P73717-10UG
5 μg
£ POA
HY-P73717-5UG
About this Product
- SKU:
- HY-P73717
- Additional Names:
- PD-L1 Protein; Canine (HEK293; Fc);Canine;HEK293
- Extra Details:
- PD-L1 Protein; Canine (HEK293; Fc) is a trans-membrane protein that is considered to be a co-inhibitory factor of the immune response. The amino acid sequence of PD-L1 is encoded by 7 exons; which form a protein of ~40 kDa. PD-L1 is a type I transmembrane protein; is part of the immunoglobulin (Ig) superfamily and is composed of IgV-like and IgC-like extracellular domains; a hydrophobic transmembrane domain and a short cytoplasmic tail composed of 30 amino acids. PD-L1 can combine with PD-1 to reduce the proliferation of PD-1 positive cells; inhibit their cytokine secretion and induce apoptosis. PD-L1 also plays an important role in various malignancies where it can attenuate the host immune response to tumor cells[1][2]. PD-L1 Protein; Canine (HEK293; Fc) is the recombinant canine-derived PD-L1 protein; expressed by HEK293 ; with C-hFc labeled tag.
- Molecular Weight:
- Approximately 70-80&140-160 kDa due to the glycosylation
- Purity:
- 98.0
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
