ACVR2B; Human/Cynomolgus (HEK293; hFc)
Product Sizes
1 mg
£ POA
HY-P72813-1MG
500 μg
£ POA
HY-P72813-500UG
2 μg
£ POA
HY-P72813-2UG
10 μg
£ POA
HY-P72813-10UG
50 μg
£ POA
HY-P72813-50UG
100 μg
£ POA
HY-P72813-100UG
About this Product
- SKU:
- HY-P72813
- Additional Names:
- ACVR2B Protein; Human/Cynomolgus (HEK293; hFc);Human;Cynomolgus;HEK293
- Extra Details:
- ACVR2B is a type II member of the TGF-β family of receptor Serine/Threonine kinases. ACVR2B binds to activins and growth differentiation factors (GDF); which in turn activate type I receptors; activating downstream molecule SMAD2/3[1]. ACVR2B Protein; Human/Cynomolgus (HEK293; hFc) is produced in HEK293 cells with a C-Terminal hFc-tag.
- Molecular Weight:
- Approximately 55-70 kDa due to the glycosylation.
- Purity:
- 97.00
- References:
- [1]Johanna Magga, et al. Systemic Blockade of ACVR2B Ligands Protects Myocardium from Acute Ischemia-Reperfusion Injury. Mol Ther. 2019 Mar 6;27(3):600-610.|[2]Oddrun Elise Olsen, et al. Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B. Cell Commun Signal. 2015 Jun 6;13:27.|[3]Rafael Barreto, et al. ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass. Sci Rep. 2017 Oct 31;7(1):14470.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Stored at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
