BDNF; Human (R125A; R127A; R128A; solution)
Product Sizes
50 μg
£ POA
HY-P72489Y-50UG
About this Product
- SKU:
- HY-P72489Y
- Additional Names:
- BDNF Protein; Human (R125A; R127A; R128A; solution);Human;E. coli
- Extra Details:
- Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that belongs to NGF-beta family. BDNF can bind to its high affinity receptor TrkB and activates signal transduction cascades (IRS1/2; PI3K; Akt)[1]. BDNF can also bind to the p75NTR; but the affinity for the p75NTR receptor is lower than for TrkB[2]. BDNF is a neurotransmitter modulator; and is vital in maturation; survival and differentiation of neuronal populations during development. BDNF also participates in neuronal plasticity; which is essential for learning and memory. BDNF is widely expressed in the CNS[1]. BDNF Protein; Human (R125A;R127A;R128A) is a recombinant human BDNF (A19-R247) with R125A; R127A; R128A mutations; and without tag; which is produced in E.coli.
- Molecular Weight:
- Approximately 28 kDa; based on SDS-PAGE under reducing conditions.
- Purity:
- 98.0
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Stored at -80[o]C for 1 year
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
