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Proteins and Peptides

BDNF; Human/Mouse/Rat

Product Sizes
2 μg
£ POA
HY-P7116A-2UG
100 μg
£ POA
HY-P7116A-100UG
10 μg
£ POA
HY-P7116A-10UG
50 μg
£ POA
HY-P7116A-50UG
About this Product
SKU:
HY-P7116A
Additional Names:
BDNF Protein; Human/Mouse/Rat;Mouse;Rat;Human;E. coli
Extra Details:
Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that belongs to NGF-beta family. BDNF can bind to its high affinity receptor TrkB and activates signal transduction cascades (IRS1/2; PI3K; Akt)[1]. BDNF can also bind to the p75NTR; but the affinity for the p75NTR receptor is lower than for TrkB[2]. BDNF is a neurotransmitter modulator; and is vital in maturation; survival and differentiation of neuronal populations during development. BDNF also participates in neuronal plasticity; which is essential for learning and memory. BDNF is widely expressed in the CNS[1]. BDNF Protein; Human is a recombinant human BDNF (H129-R247) without tag; which is produced in E.coli.
Molecular Weight:
Approximately 14-19 kDa; based on SDS-PAGE under reducing conditions.
Purity:
98.0
Shipping Conditions:
Ambient
Storage Conditions:
Stored at -20[o]C for 2 years
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
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