HVEM/TNFRSF14; Rhesus macaque (HEK293; Fc)
Product Sizes
Get quote
£ POA
HY-P70951-1EACH
About this Product
- SKU:
- HY-P70951
- Additional Names:
- HVEM/TNFRSF14 Protein; Rhesus macaque (HEK293; Fc);Rhesus Macaque;HEK293
- Extra Details:
- HVEM (herpes virus entry mediator; TNFRSF14; CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT; stimulating lymphocyte proliferation; activation; and inducing inflammatory reactions. While; HVEM binds to CD160 and BTLA; inhibiting T- and B-lymphocyte activation and proliferation[2][3]. HVEM/TNFRSF14 Protein; Rhesus macaque (HEK293; Fc) is a recombinant protein with a C-Terminal Fc label; It consists of 167 amino acids (P37-V203) and is produced in HEK293 cells.
- Molecular Weight:
- Approximately 60 kDa; based on SDS-PAGE under reducing conditions.
- References:
- [1]Ma B, et al. High expression of HVEM is associated with improved prognosis in intrahepatic cholangiocarcinoma. Oncol Lett. 2021 Jan;21(1):69.|[2]Yu X, et al. BTLA/HVEM Signaling: Milestones in Research and Role in Chronic Hepatitis B Virus Infection. Front Immunol. 2019 Mar 29;10:617.|[3]Rodriguez-Barbosa JI, et al. HVEM, a cosignaling molecular switch, and its interactions with BTLA, CD160 and LIGHT. Cell Mol Immunol. 2019 Jul;16(7):679-682.|[4]Cai G, et al. Amelioration of myocarditis by HVEM-overexpressing dendritic cells through induction of IL-10-producing cells. Cardiovasc Res. 2009 Dec 1;84(3):425-33.
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
