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Proteins and Peptides

Crotamine (TFA)

Product Sizes
1 mg
£ POA
HY-P5159A-1MG
5 mg
£ POA
HY-P5159A-5MG
10 mg
£ POA
HY-P5159A-10MG
About this Product
SKU:
HY-P5159A
Extra Details:
Crotamine TFA is a Na+ channel modulator. Crotamine is a 42 amino acid toxin cross-linked by three disulfide bridges. Crotamine has analgesic activity. Crotamine also interacts with lipid membranes and shows myonecrotic activity. Crotamine can be isolated from Crotalus durissus terrificus venom[1][2].
Molecular Weight:
4883.73 (free base)
Purity:
98.06
References:
[1]Nicastro G, et al. Solution structure of crotamine, a Na+ channel affecting toxin from Crotalus durissus terrificus venom. Eur J Biochem. 2003 May;270(9):1969-79.|[2]Kerkis I, et al. Biological versatility of crotamine--a cationic peptide from the venom of a South American rattlesnake. Expert Opin Investig Drugs. 2010 Dec;19(12):1515-25.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Pathway:
Membrane Transporter/Ion Channel
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