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Proteins and Peptides

BmP02

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HY-P5157-1EACH
About this Product
SKU:
HY-P5157
Extra Details:
BmP02 is a selective Kv1.3 channel blocker and a highly-selective Kv4.2 modulator; which can be isolated from Chinese scorpion (Buthus martensi Karsch) venom. BmP02 also delays the inactivation of Kv4.2 in HEK293T cells; with an EC50 value of ~850 nM. BmP02 inhibits the transient outward potassium currents (Ito) in ventricular muscle cells[1][2].
Molecular Weight:
2949.35
References:
[1]Wu B, et al. Mapping the Interaction Anatomy of BmP02 on Kv1.3 Channel. Sci Rep. 2016 Jul 11;6:29431.|[2]Wu B, et al. BmP02 Atypically Delays Kv4.2 Inactivation: Implication for a Unique Interaction between Scorpion Toxin and Potassium Channel. Toxins (Basel). 2016 Sep 27;8(10):280.
Research Area:
Neurological Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
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