BDS-I
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HY-P5156-1EACH
About this Product
- SKU:
- HY-P5156
- CAS Number:
- 207621-38-3
- Extra Details:
- BDS-I known as blood depressing substance; is a marine toxin which can be extracted from Anemonia sulcata. BDS-I is a specific inhibitor of Potassium Channel; targeting to Kv3.4. BDS-I inhibits Aβ1-42-induced enhancement of KV3.4 activity; caspase-3 activation; and abnormal nuclear morphology of NGF-differentiated PC-12 cells. BDS-I reverts the Aβ peptide-induced cell death[1].
- Molecular Weight:
- 4708.34
- References:
- [1]Ciccone R, et al. Synthesis and Pharmacological Evaluation of a Novel Peptide Based on聽Anemonia sulcata聽BDS-I Toxin as a New KV3.4 Inhibitor Exerting a Neuroprotective Effect Against Amyloid-尾 Peptide. Front Chem. 2019 Jul 9;7:479.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
