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Proteins and Peptides

D-Pro-Phe-Arg-Chloromethylketone

Product Sizes
1 mg
£ POA
HY-P4245-1MG
10 mg
£ POA
HY-P4245-10MG
5 mg
£ POA
HY-P4245-5MG
About this Product
SKU:
HY-P4245
CAS Number:
88546-74-1
Extra Details:
D-Pro-Phe-Arg-Chloromethylketone is a serine protease inhibitor and covalent enzyme inactivator. D-Pro-Phe-Arg-Chloromethylketone binds to the active site of KLK1 to form a covalent complex. D-Pro-Phe-Arg-Chloromethylketone inhibits staphylokinase-dependent activation of plasminogen. D-Pro-Phe-Arg-Chloromethylketone is applicable to research related to thrombosis and inflammation[1][2].
Molecular Weight:
450.96
Purity:
99.51
References:
[1]Katrin F Nickel, et al. Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases. Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):13-20.
Research Area:
Infection
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture and light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Pathway:
Immunology/Inflammation;Metabolic Enzyme/Protease
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