Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)
Product Sizes
5 mg
£ POA
HY-P4086-5MG
10 mg
£ POA
HY-P4086-10MG
1 mg
£ POA
HY-P4086-1MG
About this Product
- SKU:
- HY-P4086
- CAS Number:
- 1678417-57-6
- Extra Details:
- Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is a cell-penetrating peptide that is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) binds to nAChR on neuronal cells to mediate receptor-mediated endocytosis and targeted siRNA delivery. Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) protects complexed siRNA from degradation; enhances transcellular siRNA delivery in neuronal cells; and promotes efficient; pecific gene silencing. Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) can be used for the researches of neurological disease and cancer[1][2].
- Molecular Weight:
- 4843.45
- Purity:
- 98.42
- References:
- [1]Rassu G, et al. Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer's therapy. Colloids Surf B Biointerfaces. 2017 Apr 1;152:296-301.|[2]Margus H, et al. Cell-penetrating peptides as versatile vehicles for oligonucleotide delivery. Mol Ther. 2012 Mar;20(3):525-33.
- Research Area:
- Cancer;Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- Anti-infection
