Glycerol kinase; microorganism
Product Sizes
500 U
£ POA
HY-P2917-500U
1 KU
£ POA
HY-P2917-1KU
About this Product
- SKU:
- HY-P2917
- Additional Names:
- GyK
- Application:
- Electron Microscopy
- CAS Number:
- 9030-66-4
- Extra Details:
- Glycerol kinase; microorganism acts as a NR4A1 inhibitor with enzymatic activity. It directly binds to and inhibits the transcription factor NR4A1; thereby negatively regulating hepatic gluconeogenesis and reducing blood glucose levels. Glycerol kinase; microorganism positively regulates UCP1 expression via partial dependence on the β-adrenergic receptor-cAMP-CREB pathway; promotes browning of white adipose tissue and thermogenesis; and further modulates intracellular fatty acid composition and energy metabolism. In diabetic mouse models; overexpression of Glycerol kinase effectively antagonizes NR4A1-induced hyperglycemia; demonstrating potential for improving glucose homeostasis. Glycerol kinase; microorganism can be used for studies on diabetes and obesity[1][2].
- Molecular Weight:
- N/A
- Purity:
- 90.0
- References:
- [1]Yeh JI, et al. Structural characterizations of glycerol kinase: unraveling phosphorylation-induced long-range activation. Biochemistry. 2009 Jan 20;48(2):346-56.
- Research Area:
- Inflammation/Immunology;Metabolic Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Pathway:
- Metabolic Enzyme/Protease
