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Proteins and Peptides

Creatinase (Recombinant)

Product Sizes
5 KU
£ POA
HY-P2893A-5KU
1 KU
£ POA
HY-P2893A-1KU
About this Product
SKU:
HY-P2893A
Additional Names:
Creatine amidinohydrolase
CAS Number:
37340-58-2
Extra Details:
Creatinase (Recombinant) is a hydrolase responsible for catalyzing the hydrolysis of creatine (HY-W010388) into sarcosine (HY-101037) and urea (HY-Y0271). Creatinase (Recombinant) can be used in conjunction with creatinine deiminase (HY-P2838) and sarcosine oxidase (HY-P2861) in an enzyme cascade reaction to measure creatinine (HY-B0504) levels in blood and urine. Creatinase (Recombinant) is the rate-limiting enzyme in this enzymatic cascade; and the enzymatic quantification of creatinine is an important method for evaluating kidney function[1][2].
References:
[1]Schumann J, et al. Stabilization of creatinase from Pseudomonas putida by random mutagenesis. Protein Sci. 1993 Oct;2(10):1612-20. |[2]Bai X, et al. Improved thermostability of creatinase from Alcaligenes Faecalis through non-biased phylogenetic consensus-guided mutagenesis. Microb Cell Fact. 2020 Oct 17;19(1):194.
Research Area:
Metabolic Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 2 years
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
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