Atrial natriuretic factor (1-28) (human; porcine)
Product Sizes
1 mg
£ POA
HY-P2281-1MG
500 μg
£ POA
HY-P2281-500UG
About this Product
- SKU:
- HY-P2281
- Additional Names:
- Atrial natriuretic peptide (1-28)
- Application:
- Electron Microscopy
- CAS Number:
- 91917-63-4
- Extra Details:
- Atrial natriuretic factor (1-28) (human; porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human; porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human; porcine) increases cGMP levels in RMIC cells with an IC50 of 1.2 nM[1][2][3].
- Molecular Weight:
- 3080.46
- References:
- [1]B M Fontoura, et al. Atrial natriuretic factor receptors in cultured renomedullary interstitial cells. Am J Physiol. 1990 Apr;258(4 Pt 1):C692-9.|[2]T T Tan, et al. ANF(1-28) is a potent suppressor of pro-opiomelanocortin (POMC) mRNA but a weak inhibitor of beta EP-LI release from AtT-20 cells. J Endocrinol. 1994 Nov;143(2):R1-4.|[3]D M Pollock, et al. Beneficial effect of the ANF analog A68828 on recovery from ischemic acute renal failure. Ren Fail. 1992;14(2):141-6.
- Research Area:
- Metabolic Disease; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
