Cotadutide
Product Sizes
5 mg
£ POA
HY-P2231-5MG
10 mg
£ POA
HY-P2231-10MG
About this Product
- SKU:
- HY-P2231
- Additional Names:
- MEDI0382
- Application:
- Immunoprecipitation
- CAS Number:
- 1686108-82-6
- Extra Details:
- Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM; respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control; and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D)[1][2][3].
- Molecular Weight:
- 3728.09
- Purity:
- 99.11
- References:
- [1]Henderson SJ,et al. Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates.Diabetes Obes Metab. 2016 Dec;18(12):1176-1190. |[2]Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. Nat Metab. 2020 May;2(5):413-431.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- GPCR/G Protein
