Cortistatin-29 (rat)
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HY-P2150-1EACH
About this Product
- SKU:
- HY-P2150
- CAS Number:
- 1815618-17-7
- Extra Details:
- Cortistatin-29 is a neuropeptide. Cortistatin-29 alleviates neuropathic pain. Cortistatin-29 binds all somatostatin (SS) receptor subtypes with high affinity and shows IC50 values of 2.8 nM; 7.1 nM; 0.2 nM; 3.0 nM; 13.7 nM for SSTR1; SSTR2; SSTR3; SSTR4; SSTR5; respectively. Cortistatin-29 shows anti-fibrotic effects[1][2][3][4].
- Molecular Weight:
- 3540.04
- References:
- [1]Falo CP, et al. The Neuropeptide Cortistatin Alleviates Neuropathic Pain in Experimental Models of Peripheral Nerve Injury. Pharmaceutics. 2021 Jun 24;13(7):947.|[2]Baranowska B, et al. Direct effect of cortistatin on GH release from cultured pituitary cells in the rat. Neuro Endocrinol Lett. 2006 Feb-Apr;27(1-2):153-6.|[3]Spier AD, et al. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res Brain Res Rev. 2000 Sep;33(2-3):228-41.|[4]Benitez R, et al. Cortistatin regulates fibrosis and myofibroblast activation in experimental hepatotoxic- and cholestatic-induced liver injury. Br J Pharmacol. 2022 May;179(10):2275-2296.
- Research Area:
- Inflammation/Immunology; Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
