Cyclic MKEY (TFA)
Product Sizes
10 mg
£ POA
HY-P1949A-10MG
5 mg
£ POA
HY-P1949A-5MG
About this Product
- SKU:
- HY-P1949A
- Application:
- Antibody Microarray
- Extra Details:
- Cyclic MKEY TFA is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation; which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY TFA also protects against stroke-induced brain injury in mice[1][2].
- Molecular Weight:
- 2530.87 (free acide)
- Purity:
- 98.47
- References:
- [1]Fan Y,et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016 Sep 15;5(9). pii: e003615.|[2]Iida Y, et al. Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):718-26.
- Research Area:
- Cancer; Cardiovascular Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture and light; under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- GPCR/G Protein;Immunology/Inflammation
