Apelin-13
Product Sizes
1 mg
£ POA
HY-P1944-1MG
10 mg
£ POA
HY-P1944-10MG
5 mg
£ POA
HY-P1944-5MG
About this Product
- SKU:
- HY-P1944
- Application:
- Electron Microscopy
- CAS Number:
- 217082-58-1
- Extra Details:
- Apelin-13 is an endogenous ligand for the G-protein coupled receptor angiotensin II protein J (APJ); activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. Apelin-13 is widely distributed in the central and peripheral nervous systems. Apelin-13 has vasodilatory and antihypertensive effects. Apelin-13 also can be used for researching type 2 diabetes and metabolic syndrome[1][2][3].
- Molecular Weight:
- 1550.83
- Purity:
- 98.11
- References:
- [1]Tatemoto, K., Hosoya, M., Habata, Y., et al. Isolation and characterizaton of a novel endogenous peptide ligand for the human APJ receptor. Biochemical and Biophysical Research Communications 251, 471-476 (1998).|[2]Li M,et al. Apelin 13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high fat diet. Mol Med Rep. 2018 Dec;18(6):5784-5790.|[3]Yamaleyeva LM, et al. Apelin-13 in blood pressure regulation and cardiovascular disease. Curr Opin Nephrol Hypertens. 2016 Sep;25(5):396-403.|[4]Wang Y, et al. Apelin-13 regulates electrical activity in the globus pallidus and induces postural changes in rats. Neural Regen Res. 2021 Nov;16(11):2264-2268.
- Research Area:
- Metabolic Disease; Cardiovascular Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- GPCR/G Protein
