Cyclo(L-Phe-L-Pro)
Product Sizes
25 mg
£ POA
HY-P1934A-25MG
100 mg
£ POA
HY-P1934A-100MG
50 mg
£ POA
HY-P1934A-50MG
About this Product
- SKU:
- HY-P1934A
- CAS Number:
- 3705-26-8
- Extra Details:
- Cyclo(L-Phe-L-Pro); isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide[1]. Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation[2]. Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay[3].
- Molecular Weight:
- 244.29
- Purity:
- 99.75
- References:
- [1]Katrin Ström, et al. <i>Lactobacillus plantarum</i> MiLAB 393 Produces the Antifungal Cyclic Dipeptides Cyclo(L-Phe-L-Pro) and Cyclo(L-Phe-trans-4-OH-L-Pro) and 3-Phenyllactic Acid. Appl Environ Microbiol. 2002 Sep;68(9):4322-7.|[2]Wooseong Lee, et al. Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity. Nat Commun. 2018 Apr 23;9(1):1606.|[3]Keyong Ho Lee, et al. Radioprotective effect of cyclo(L-phenylalanyl-L-prolyl) on irradiated rat lung. J Microbiol Biotechnol. 2008 Feb;18(2):369-76.|[4]Li H, et al. Inhibition mechanism of cyclo (L-Phe-L-Pro) on early stage Staphylococcus aureus biofilm and its application on food contact surface[J]. Food Bioscience, 2022, 49: 101968.
- Research Area:
- Cancer; Infection; Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- Anti-infection;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
