Cyclo(Phe-Pro)
Product Sizes
50 mg
£ POA
HY-P1934-50MG
10 mg
£ POA
HY-P1934-10MG
100 mg
£ POA
HY-P1934-100MG
5 mg
£ POA
HY-P1934-5MG
25 mg
£ POA
HY-P1934-25MG
About this Product
- SKU:
- HY-P1934
- Additional Names:
- Cyclo(phenylalanylprolyl); A-64863
- CAS Number:
- 14705-60-3
- Extra Details:
- Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I; inhibiting RIG-I polyubiquitination; suppressing IRF-3 activation; and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways; bacterial virulence gene expression; and plant antioxidant systems; making it a promising candidate for research in viral infections; bacterial virulence regulation; and agricultural stress resistance[1][2][3].
- Molecular Weight:
- 244.29
- Purity:
- 99.22
- References:
- [1]Lee W, et al. Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity. Nat Commun. 2018 Apr 23;9(1):1606.|[2]Bina XR, et al. The cyclic dipeptide cyclo(Phe-Pro) inhibits cholera toxin and toxin-coregulated pilus production in O1 El Tor Vibrio cholerae. J Bacteriol. 2010 Jul;192(14):3829-32.|[3]Wang Y, et al. Novel application of cyclo(-Phe-Pro) in mitigating aluminum toxicity through oxidative stress alleviation in wheat roots. Environ Pollut. 2024 Dec 15;363(Pt 2):125241.
- Research Area:
- Infection
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- Anti-infection;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
