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Proteins and Peptides

L-Asparaginase

Product Sizes
25 mg
£ POA
HY-P1923-25MG
10 mg
£ POA
HY-P1923-10MG
5 mg
£ POA
HY-P1923-5MG
1 mg
£ POA
HY-P1923-1MG
50 mg
£ POA
HY-P1923-50MG
100 mg
£ POA
HY-P1923-100MG
About this Product
SKU:
HY-P1923
Additional Names:
L-​ASNase
Application:
Antibody Microarray
CAS Number:
9015-68-3
Extra Details:
L-Asparaginase (L-ASNase) is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine; and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1].
Molecular Weight:
34000 (monomer)
Purity:
99.91
References:
[1] Ilaria M Michelozzi, et al. Acute myeloid leukaemia niche regulates response to L-asparaginase. Br J Haematol. 2019 Aug;186(3):420-430. doi: 10.1111/bjh.15920. |[2]T Ueno, et al. Cell cycle arrest and apoptosis of leukemia cells induced by L-asparaginase. Leukemia. 1997 Nov;11(11):1858-61.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 2 years
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Pathway:
Apoptosis;Cell Cycle/DNA Damage
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