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Proteins and Peptides

CLIP (86-100)

Product Sizes
1 mg
£ POA
HY-P1826-1MG
5 mg
£ POA
HY-P1826-5MG
About this Product
SKU:
HY-P1826
CAS Number:
648881-58-7
Extra Details:
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].
Molecular Weight:
1674.10
Purity:
98.39
References:
[1]van Luijn MM, et al. Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia. Oncoimmunology. 2015 Jan 7;3(12):e941737. eCollection 2014 Dec.|[2]Thayer WP, et al. Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules. J Immunol. 1999 Feb 1;162(3):1502-9.
Research Area:
Cancer; Inflammation/Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Pathway:
Immunology/Inflammation
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