Angiotensin II (5-8); human
Product Sizes
5 mg
£ POA
HY-P1769-5MG
25 mg
£ POA
HY-P1769-25MG
10 mg
£ POA
HY-P1769-10MG
About this Product
- SKU:
- HY-P1769
- Application:
- Electron Microscopy
- CAS Number:
- 34233-50-6
- Extra Details:
- Angiotensin II (5-8); human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II[1]. Angiotensin II binds the AT II type 1 (AT1) receptor; stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[2][3].
- Molecular Weight:
- 512.60
- Purity:
- 99.74
- References:
- [1]Guethe LM, et al. Angiotensin (5-8) modulates nociception at the rat periaqueductal gray via the NO-sGC pathway and an endogenous opioid. Neuroscience. 2013 Feb 12;231:315-27.|[2]De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411.|[3]Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5.
- Research Area:
- Metabolic Disease; Endocrinology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture and light; under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- GPCR/G Protein
