Astin C
Product Sizes
5 mg
£ POA
HY-P1680-5MG
1 mg
£ POA
HY-P1680-1MG
About this Product
- SKU:
- HY-P1680
- Additional Names:
- Asterin
- CAS Number:
- 148057-23-2
- Extra Details:
- Astin C (Asterin) is a cyclopeptide that can be extracted from Aster tataricus. Astin C has anti-inflammatory and anti-cancer activities. Astin C can specifically inhibit the cGAS-STING signaling pathway; block the recruitment of IRF3 to the STING signalosome; and thus inhibit the innate inflammatory response. Astin C can be used in the research of autoimmune diseases and cancers[1][2][3].
- Molecular Weight:
- 570.47
- Purity:
- 99.47
- References:
- [1]Antoine Vassaux, et al. Astin C Production by the Endophytic Fungus Cyanodermella asteris in Planktonic and Immobilized Culture Conditions. Biotechnol J. 2019 Aug;14(8):e1800624. |[2]Li S, et al. The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING. Cell Rep. 2018 Dec 18;25(12):3405-3421.e7.|[3]Morita H, et al. Cyclic peptides from higher plants. XXVIII. Antitumor activity and hepatic microsomal biotransformation of cyclic pentapeptides, astins, from Aster tataricus. Chem Pharm Bull (Tokyo). 1996 May;44(5):1026-32.
- Research Area:
- Cancer; Infection; Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- Immunology/Inflammation
