APETx2
Product Sizes
5 mg
£ POA
HY-P1346-5MG
25 mg
£ POA
HY-P1346-25MG
10 mg
£ POA
HY-P1346-10MG
About this Product
- SKU:
- HY-P1346
- CAS Number:
- 713544-47-9
- Extra Details:
- APETx2; a sea anemone peptide from Anthopleura elegantissima; is a selective and reversible ASIC3 inhibitor; with an IC50 of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain[1][2].
- Molecular Weight:
- 4561.00
- References:
- [1]Sylvie Diochot, et al. A New Sea Anemone Peptide, APETx2, Inhibits ASIC3, a Major Acid-Sensitive Channel in Sensory Neurons. EMBO J. 2004 Apr 7;23(7):1516-25.|[2]Jerzy Karczewski, et al. Reversal of Acid-Induced and Inflammatory Pain by the Selective ASIC3 Inhibitor, APETx2. Br J Pharmacol. 2010 Oct;161(4):950-60.
- Research Area:
- Inflammation/Immunology; Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
