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Proteins and Peptides

CNI103

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HY-P10889-1EACH
About this Product
SKU:
HY-P10889
CAS Number:
2366279-86-7
Extra Details:
CNI103 is a highly potent and metabolically stable cell-permeable peptide inhibitor of calcineurin. CNI103 selectively blocks the interaction between calcineurin and NFATc3 (KD=16 nM); thereby preventing NFATc3 activation in vitro and in vivo. CNI103 can be used to study acute respiratory distress syndrome (ARDS) and other inflammatory diseases[1].
Molecular Weight:
2565.80
References:
[1]Dougherty PG, et al. A Peptidyl Inhibitor that Blocks Calcineurin-NFAT Interaction and Prevents Acute Lung Injury. J Med Chem. 2020 Nov 12;63(21):12853-12872.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
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