AH-D peptide
Product Sizes
10 mg
£ POA
HY-P10862-10MG
5 mg
£ POA
HY-P10862-5MG
1 mg
£ POA
HY-P10862-1MG
About this Product
- SKU:
- HY-P10862
- Application:
- Antibody Microarray
- Extra Details:
- AH-D peptide is a brain-penetrant antiviral agent disrupting highly curved lipid membranes. AH-D peptide exhibits broad-spectrum antiviral activity against ZIKV; Dengue virus; Chikungunya virus; yellow fever virus and Japanese encephalitis virus; with IC50 values of 11.9; 12.5; 35.7; 206 and 136 nM; respectively. AH-D peptide reduces the viral load in the brain; suppresses inflammation; protects neurons; and does not damage the blood brain barrier. AH-D peptide restores antitumor immunity by decreasing circulating PD-L1+ exosomes; reducing intratumoral immunosuppressive cells (regulatory T cells; myeloid-derived suppressor cells); and enhancing T cell function. AH-D peptide inhibits membrane-enveloped viruses and cancer cell metastasis in vivo. AH-D peptide exhibits no immunogenicity and has negligible effects on normal tissues. AH-D peptide can be used for research in Zika virus and other mosquito-borne viruses; cancer immunotherapy and metastasis[1][2].
- Molecular Weight:
- 3283.75
- Purity:
- 99.32
- References:
- [1]Sol Shin, et al. Curvature-sensing peptide inhibits tumour-derived exosomes for enhanced cancer immunotherapy. Nat Mater. 2023 May;22(5):656-665.
- Research Area:
- Cancer;Infection
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
