B7-33
Product Sizes
50 mg
£ POA
HY-P10728-50MG
5 mg
£ POA
HY-P10728-5MG
1 mg
£ POA
HY-P10728-1MG
10 mg
£ POA
HY-P10728-10MG
25 mg
£ POA
HY-P10728-25MG
About this Product
- SKU:
- HY-P10728
- CAS Number:
- 1818415-56-3
- Extra Details:
- B7-33 is a single-chain relaxin mimetic and a selective relaxin receptor 1 (RXFP1) agonist. B7-33 phosphorylates ERK1/2 without inducing activation of the cAMP signaling pathway. B7-33 exhibits anti-fibrotic and cardioprotective activities. B7-33 can be used in the research of vascular diseases such as cardiomyopathy; myocardial infarction and fibrosis[1][2].
- Molecular Weight:
- 2986.54
- Purity:
- 99.31
- References:
- [1]Alam F, et al. The single-chain relaxin mimetic, B7-33, maintains the cardioprotective effects of relaxin and more rapidly reduces left ventricular fibrosis compared to perindopril in an experimental model of cardiomyopathy. Biomed Pharmacother. 2023 Apr;160:114370.|[2]Hossain MA, et al. A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1. Chem Sci. 2016 Jun 1;7(6):3805-3819.
- Research Area:
- Cardiovascular Disease;Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
