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Proteins and Peptides

AIP-II

Product Sizes
5 mg
£ POA
HY-P10486-5MG
10 mg
£ POA
HY-P10486-10MG
1 mg
£ POA
HY-P10486-1MG
About this Product
SKU:
HY-P10486
CAS Number:
200010-31-7
Extra Details:
AIP-II is a cyclic peptide signaling molecule for quorum sensing; which is produced by Staphylococcus aureus. AIP-II potently inhibits AgrC-III in Methicillin (HY-121544)-resistant type III Staphylococcus aureus strain AH1747; with an IC50 of 0.532 nM. AIP-II binds to the AgrC-II receptor and regulates virulence gene expression in Staphylococcus aureus[1][2].
Molecular Weight:
878.99
Purity:
98.04
References:
[1]Tal-Gan Y, et al., Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus. J Am Chem Soc. 2013 Dec 11;135(49):18436-44.
Research Area:
Infection
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
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